Paraumbilical hernia repair during caesarean section; maternal and neonatal outcome

A prospective study to evaluate the outcome of combined cesarean section and paraumblical hernia repair in tertiary referral university hospital. Patients and methods: 48 patients undergoing Cesarean section combined with paraumbilical hernia repair versus 100 patients undergoing cesarean section alone. Main Outcome Measures: Operation time, Apgar Score, blood loss, uterine atony, breast feeding initiation, pain sensation, periparturn complications, prolonged lochia [more than 42 days], deep venous thrombosis, hospital stay, hernia recurrence, and patient choice. The combined procedure consumed significantly longer time than cesarean section alone in the mesh hernioplasty subgroup. There were no major complications. Apgar Score, uterine atony, initiation of breastfeeding, prolonged tochia, wound infection and hospital stay did not differ significantly from those of controls. Pain at hernia site repair in two patients, one hernia recurred in the primary repair subgroup during follow up period which reach up to 3 years. All hernia group patients reported that they prefere the combined operation. Combined cesarean section and paraumbilical hernia repair had the advantage of single incision, single anesthesia, and single hospital stay. The combination approach proved to be safe, effective, and well accepted

Erectile dysfunction among workers occupationally exposed to ammonia

Numerous psychological factors can disrupt the normal physiologic functions involved in the erectile mechanism. In the past, most cases of erectile dysfunction [ED] were thought to be of psychological origin, but it is now recognized that the majority of cases, especially in the elderly, have an organic cause

Objective: in this study, we aimed to determine whether occupational exposure to ammonia, as a risk factor, can induces erectile dysfunction [ED] among workers occupationally exposed to ammonia

Methodology: we performed a standard ED evaluation that included full history, physical examination, estimation of serum testosterone [T] and prolactin [PRL] levels and penile Duplex ultrasonography [PDU] for the suspected cases. Our results showed Hypotestosteronemia in [10%], but in the contrary, hyperprolactinemia was not detected in any of the studied workers. Thirty percent [30%] of the studied exposed workers showed mild penile venous leak

Conclusion: according to our findings, there is a high prevalence of ED in exposed workers to ammonia. However, the mechanism of occurrence and the physiological mechanism of ammonia induced erectile dysfunction is not well documented. We recommended further studies to clarify the mechanism of action of the long term occupational exposure to ammonia on the sexual behaviour and sexual feeling among males exposed workers

Strategies for myocardial protection during cardiopulmonary by-pass in congenital cyanotic heart disease guided by troponin I

Forty cyanotic infants with age ranging from six to 24 months and body weights ranged from six to 11 kg were included in this study and the surgical correction of their congenital cardiac problems was done under cardiopulmonary bypass. The selected cases were divided into four equal groups according to the concentration of KCl added to the blood cardioplegia and the intravenous administration of aprotinin. In group A, 30 mEq KCl/L was added to the blood cardioplegic solution. In group B, 40 mEq KCl/L was added to the blood cardioplegic solution. In group C, together with blood cardioplegia as group A, the patients received intravenous high dose regimen of aprotinin. In group D, the patients received the same intravenous regimen of aprotinin as group C, but with blood cardioplegia as group B. The serum level of cardiac troponin I [cTnI] was assessed as an index of myocardial injury simultaneously with serum sodium, potassium and calcium. These variables were measured in different periods of the study, starting from period I [baseline value, before induction of anesthesia] and ending by period VII [after the transfer to intensive care unit]. The total dosage of inotropic supporters [adrenaline and dopamine], vasodilators [sodium nitroprusside] and myocardial behavior were monitored in all studied cases. The study concluded that the intravenous administration of the high dose regimen of aprotinin with the addition of 40 mEq/L KCl to the blood cardioplegic solution was one of the best strategies for myocardial protection during cardiopulmonary bypass in cyanotic infants

Hepatotoxic effect of concomitant administration of acetaminophen [paracetamol] and ethanol in rats

Five groups of albino rats, 10 animals each, were used in this work. Animals of group I were given ethanol, those of group II were given acetaminophen, while in group III and IV animals were given both ethanol and acetaminophen concomitantly. The dose of acetaminophen was doubled to animals of group IV. The fifth group was served as a control. Histopathological and histochemical studies of the liver showed that the hepatotoxic effect of acetaminophen or ethanol when each was given alone is more than when both substances were given concomitantly